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N,S-chelating triazole-thioether ligand for highly efficient palladium-catalyzed Suzuki reaction
- Yan, Qiong, Zheng, Lei, Li, Miaomiao, Chen, Yunfeng
- Journal of catalysis 2019 v.376 pp. 101-105
- Suzuki reaction, bromides, catalysts, catalytic activity, chlorides, crystal structure, energy, iodides, ligands, organoiodine compounds, palladium, redox potential
- 1,2,3-Triazole-thioether compounds could serve as efficient ligands for Pd-catalyzed Suzuki reactions of various aryl iodides, bromides and chlorides. The reactions feature wide substrate scope and mild reaction conditions. Besides, shorter reaction time, lower catalyst loadings and quantitative yields with a turnover-frequency (TOF) value of up to 11,880 h−1 are other advantageous of this attractive protocol. The crystal structure analyses and computational studies revealed that the higher catalytic activity of the corresponding chelated palladium complex ascribed to the lower energy gap and the lower redox potential.