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Construction of a fluorescent probe for selectively detecting singlet oxygen with a high sensitivity and large concentration range based on a two-step cascade sensing reaction

Author:
Long, Lingliang, Yuan, Xiangqi, Cao, Siyu, Han, Yuanyuan, Liu, Weiguo, Chen, Qian, Gong, Aihua, Wang, Kun
Source:
Chemical communications 2019 v.55 no.58 pp. 8462-8465
ISSN:
1364-548X
Subject:
adverse effects, chemical compounds, chemical reactions, fluorescent dyes, neoplasms, singlet oxygen
Abstract:
A novel fluorescent probe XQ-1 for selectively detecting ¹O₂ on the basis of a two-step cascade reaction has been rationally constructed. The probe responded to ¹O₂ not only showing a high sensitivity, but also displaying a large concentration range, which means that the probe can be used as a powerful tool to monitor the efficacy of PDT toward cancer and concurrently track the adverse effects on healthy cells.
Agid:
6539590