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Phytochemicals in Prostate Cancer: From Bioactive Molecules to Upcoming Therapeutic Agents
- Salehi, Bahare, Fokou, Patrick Valere Tsouh, Yamthe, Lauve Rachel Tchokouaha, Tali, Brice Tchatat, Adetunji, Charles Oluwaseun, Rahavian, Amirhossein, Mudau, Fhatuwani Nixwell, Martorell, Miquel, Setzer, William N., Rodrigues, Célia F., Martins, Natália, Cho, William C., Sharifi-Rad, Javad
- Nutrients 2019 v.11 no.7
- alkaloids, bioactive compounds, chemoprevention, medicinal plants, men, new drugs, phenolic compounds, phytochemicals, plant extracts, prostatic neoplasms, steroids, terpenoids, therapeutics
- Prostate cancer is a heterogeneous disease, the second deadliest malignancy in men and the most commonly diagnosed cancer among men. Traditional plants have been applied to handle various diseases and to develop new drugs. Medicinal plants are potential sources of natural bioactive compounds that include alkaloids, phenolic compounds, terpenes, and steroids. Many of these naturally-occurring bioactive constituents possess promising chemopreventive properties. In this sense, the aim of the present review is to provide a detailed overview of the role of plant-derived phytochemicals in prostate cancers, including the contribution of plant extracts and its corresponding isolated compounds.