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Synthesis of chroman-4-one and indanone derivatives via silver catalyzed radical ring opening/coupling/cyclization cascade
- Liu, Qiang, Xie, Guanqun, Wang, Qiang, Mo, Zhendong, Li, Chen, Ding, Shujiang, Wang, Xiaoxia
- Tetrahedron 2019
- aldehydes, catalytic activity, chemical structure, cyclization reactions, indans, silver
- A variety of chroman-4-one and indanone derivatives were conveniently synthesized from readily available cyclopropanols and alkenyl aldehydes via a silver catalyzed radical ring-opening/coupling/cyclization cascade. The reaction proceeded under mild and neutral conditions with broad substrate scope and afforded the desired products in moderate to good yields. A probable mechanism for the cascade reaction was also proposed.