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Increased genetic variation of bovine viral diarrhea virus in dairy cattle in Poland
- Mirosław, Paweł, Polak, Mirosław
- BMC veterinary research 2019 v.15 no.1 pp. 278
- 5' untranslated regions, Bovine viral diarrhea virus 1, dairy cattle, dairy herds, diagnostic techniques, financial economics, genetic variation, genome, genotype, pathogens, phylogeny, signs and symptoms (animals and humans), vaccines, viruses, Poland
- BACKGROUND: Bovine viral diarrhea virus (BVDV) causes severe economic losses and is one of the most important viral pathogens of ruminants worldwide. The infection manifests itself in a variety of clinical symptoms. Phylogenetic studies based mainly on 5’UTR of its genome, identified many different subtypes of BVDV. Previous study indicated the predominance of BVDV-1b and BVDV-1d in Poland. The aim of this study was to genotype BVDV isolates currently circulating in Polish dairy herds. RESULTS: BVDV was detected in 30 herds. Viral subtypes were identified using sequences of the 5’UTR fragment and they were confirmed within a fragment of the Nᵖʳᵒ region. Seven subtypes of BVDV-1 species have been identified: 1b, 1 g, 1f, 1d, 1r, 1 s and 1e. CONCLUSION: The number of subtypes of BVDV in Poland evolves and 2 new subtypes have been identified for the first time. Such studies may have a positive impact on successful eradication of the virus using effective vaccines and diagnostic tests.