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Manipulation by Methylation: Garnishing mRNAs with m6Am

Author:
Doxtader, Katelyn A., Nam, Yunsun
Source:
Molecular cell 2019 v.75 no.3 pp. 417-418
ISSN:
1097-2765
Subject:
messenger RNA, methylation, transcription (genetics), transcriptome, translation (genetics)
Abstract:
In two recent publications in Molecular Cell,Boulias et al. (2019) and Sendinc et al. (2019) use complementary approaches to map m6Am modification sites transcriptome-wide and demonstrate that m6Am can repress translation while increasing the stability of a subset of low-abundance transcripts.
Agid:
6561950