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A Large-Scale Serological Survey of Toxoplasma gondii Infection Among Persons Participated in Health Screening in Yunnan Province, Southwestern China

Author:
Li, Zhao, Sun, Chun-Yi, Yang, Ren-Dan, Xu, Chang-Jun, Chen, Mei-Chen, Zhang, Yun-Jiang, Cong, Wei, Zhu, Xing-Quan, Liu, Yang, Zou, Feng-Cai
Source:
Vector borne and zoonotic diseases 2019 v.19 no.6 pp. 441-445
ISSN:
1557-7759
Subject:
Toxoplasma gondii, antibodies, blood serum, enzyme-linked immunosorbent assay, females, hospitals, humans, immunoglobulin G, immunoglobulin M, males, people, public health, screening, serological surveys, seroprevalence, toxoplasmosis, China
Abstract:
Surveys of Toxoplasma gondii infection in animals have been reported in Yunnan province, southwestern China. However, limited information is available regarding the epidemiology of T. gondii infection among persons participated in health screening in Yunnan. From January 2014 to December 2016, a large-scale and cross-sectional serological survey was conducted to reveal the seroprevalence of T. gondii infection in persons participated in health screening in three major hospitals. A total of 64,533 serum samples were collected and anti-T. gondii antibodies were examined by commercially available enzyme-linked immunosorbent assay kits. The total seroprevalence of T. gondii infection was 6.67% (4306/64,533). Of these, 3721 persons (5.77%, 3721/64,533) were positive for Immunoglobulin G (IgG) only, 473 persons (0.73%, 473/64,533) were positive for Immunoglobulin M (IgM) only, and 112 persons (0.17%, 112/64,533) were positive for both IgG and IgM. Female seroprevalence (6.83%, 3167/46,389) was higher than male (6.28%, 1139/18,144). The highest seroprevalence of T. gondii infection was found in the age range of 41–50 years (10.60%, 228/2150) (p < 0.001). The seroprevalence in 2014, 2015, and 2016 were 6.39% (1083/16,946), 6.24% (1261/20,201), and 7.16% (1962/27,386), respectively. The results showed that T. gondii infection is common in persons participated in health screening in Yunnan province, which has significant public health concern. Thus, improved integrated measures should be executed to prevent and control T. gondii infection humans and animals in Yunnan province.
Agid:
6563671