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Organocatalytic asymmetric reaction of indol-2-yl carbinols with enamides: synthesis of chiral 2-indole-substituted 1,1-diarylalkanes

Author:
Liu, Chao-You, Han, Fu-She
Source:
Chemical communications 2015 v.51 no.59 pp. 11844-11847
ISSN:
1364-548X
Subject:
catalytic activity, chemical compounds, chemical reactions
Abstract:
The chiral phosphoramide-catalyzed asymmetric reaction of indol-2-yl carbinols with enamides is presented. The method provided an efficient and novel way for the synthesis of chiral 2-indole-substituted 1,1-diarylalkane derivatives.
Agid:
6609939