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Alkene hydroboration with pinacolborane catalysed by lithium diisobutyl-tert-butoxyaluminum hydride
- Jaladi, Ashok Kumar, Shin, Won Kyu, An, Duk Keun
- RSC advances 2019 v.9 no.45 pp. 26483-26486
- alcohols, alkenes, catalytic activity, cations, hydrides, lithium, oxidation
- Here we developed a highly efficient alkene hydroboration protocol, showing that various alkyl boronates can be smoothly obtained in good yields by reacting alkenes with pinacolborane (HBpin) in the presence of 5 mol% lithium diisobutyl-tert-butoxyaluminum hydride. The coordination of aluminate ions with lithium cations allowed for effective hydride transfer during hydroboration, and the obtained boronate ester was further used for C–C coupling, trifluoroboronate salt formation, and oxidation to alcohol.