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Alkene hydroboration with pinacolborane catalysed by lithium diisobutyl-tert-butoxyaluminum hydride

Author:
Jaladi, Ashok Kumar, Shin, Won Kyu, An, Duk Keun
Source:
RSC advances 2019 v.9 no.45 pp. 26483-26486
ISSN:
2046-2069
Subject:
alcohols, alkenes, catalytic activity, cations, hydrides, lithium, oxidation
Abstract:
Here we developed a highly efficient alkene hydroboration protocol, showing that various alkyl boronates can be smoothly obtained in good yields by reacting alkenes with pinacolborane (HBpin) in the presence of 5 mol% lithium diisobutyl-tert-butoxyaluminum hydride. The coordination of aluminate ions with lithium cations allowed for effective hydride transfer during hydroboration, and the obtained boronate ester was further used for C–C coupling, trifluoroboronate salt formation, and oxidation to alcohol.
Agid:
6611952