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Dichrocephones A and B, two cytotoxic sesquiterpenoids with the unique [3.3.3] propellane nucleus skeleton from Dichrocephala benthamii
- Tian, Xinhui, Li, Li, Hu, Yanbao, Zhang, Hongwu, Liu, Yuetao, Chen, Hong, Ding, Gang, Zou, Zhongmei
- RSC advances 2013 v.3 no.21 pp. 7880-7883
- cell lines, cytotoxicity, sesquiterpenoids
- Dichrocephones A (1) and B (2), two new modhephane sesquiterpenoids containing the key core skeleton as that of modhephane sesquiterpenoids rarely encountered in nature were isolated from Dichrocephala benthamii. Dichrocephone B (2) contains a new ring system formed by the [3.3.3] propellane core structure fused to a unique oxetane ring with significant cytotoxicity against HeLa, KB and A549 cell lines.