PubAg

Main content area

Dichrocephones A and B, two cytotoxic sesquiterpenoids with the unique [3.3.3] propellane nucleus skeleton from Dichrocephala benthamii

Author:
Tian, Xinhui, Li, Li, Hu, Yanbao, Zhang, Hongwu, Liu, Yuetao, Chen, Hong, Ding, Gang, Zou, Zhongmei
Source:
RSC advances 2013 v.3 no.21 pp. 7880-7883
ISSN:
2046-2069
Subject:
cell lines, cytotoxicity, sesquiterpenoids
Abstract:
Dichrocephones A (1) and B (2), two new modhephane sesquiterpenoids containing the key core skeleton as that of modhephane sesquiterpenoids rarely encountered in nature were isolated from Dichrocephala benthamii. Dichrocephone B (2) contains a new ring system formed by the [3.3.3] propellane core structure fused to a unique oxetane ring with significant cytotoxicity against HeLa, KB and A549 cell lines.
Agid:
6644407