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Updates on immunologic correlates of vaccine-induced protection

Author:
Plotkin, Stanley A.
Source:
Vaccine 2020 v.38 no.9 pp. 2250-2257
ISSN:
0264-410X
Subject:
immune response, vaccination, vaccine development, vaccines
Abstract:
Correlates of protection (CoPs) are increasingly important in the development and licensure of vaccines. Although the study of CoPs was initially directed at identifying a single immune function that could explain vaccine efficacy, it has become increasingly clear that there are often multiple functions responsible for efficacy. This review is meant to supplement prior articles on the subject, illustrating both simple and complex CoPs.
Agid:
6741776