Jump to Main Content
Updates on immunologic correlates of vaccine-induced protection
- Plotkin, Stanley A.
- Vaccine 2020 v.38 no.9 pp. 2250-2257
- immune response, vaccination, vaccine development, vaccines
- Correlates of protection (CoPs) are increasingly important in the development and licensure of vaccines. Although the study of CoPs was initially directed at identifying a single immune function that could explain vaccine efficacy, it has become increasingly clear that there are often multiple functions responsible for efficacy. This review is meant to supplement prior articles on the subject, illustrating both simple and complex CoPs.