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RNA nanotechnology in synthetic biology
- Kim, Jongmin, Franco, Elisa
- Current opinion in biotechnology 2020 v.63 pp. 135-141
- RNA, gene expression, nanotechnology, nucleotide sequences, synthetic biology
- We review recent advances in the design and expression of synthetic RNA sequences inside cells, to regulate gene expression and to achieve spatial localization of components. We focus on approaches that exploit the programmability of the secondary and tertiary structure of RNA to build scalable and modular devices that fold spontaneously and have the capacity to respond to environmental inputs.