PubAg

Main content area

Imprinted Small RNAs Unraveled: Maternal MicroRNAs Antagonize a Paternal-Genome-Driven Gene Expression Network

Author:
Ghousein, Amani, Feil, Robert
Source:
Molecular cell 2020 v.78 no.1 pp. 3-5
ISSN:
1097-2765
Subject:
gene expression, gene expression regulation, genes, genomic imprinting, microRNA, neurons
Abstract:
Whipple et al., 2020 describe that, in neurons, a dense cluster of maternally expressed microRNAs post-transcriptionally downregulates several imprinted genes expressed from the paternal genome—an antagonistic mechanism that modulates neuronal functions and provides insights into the evolution of genomic imprinting.
Agid:
6879601