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Of Dots and Stripes: The Morse Code of Micro-C Reveals the Ultrastructure of Transcriptional and Architectural Mammalian 3D Genome Organization
- Chang, Li-Hsin, Noordermeer, Daan
- Molecular cell 2020 v.78 no.3 pp. 376-378
- chromatin, gene expression, genes, humans, mice, transcription (genetics), ultrastructure
- Using Micro-C, Hsieh et al. (2020) and Krietenstein et al. (2020) investigated 3D chromatin folding in human and mouse cells at unprecedented resolution to uncover ultra-fine-scale chromatin structures that provide direct links between genome architecture, gene expression, and gene regulation.