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A new antibacterial clerodane diterpenoid from the resinous exudate of Haplopappus uncinatus

Author:
Urzua, A., Jara, F., Tojo, E., Wilkens, M., Mendoza, L., Rezende, M.C.
Source:
Journal of ethnopharmacology 2006 v.103 no.2 pp. 297-301
ISSN:
0378-8741
Subject:
Haplopappus, medicinal plants, branches, leaves, plant exudates, chemical constituents of plants, diterpenoids, flavones, alkanes, sesquiterpenoids, medicinal properties, antibacterial properties
Abstract:
The antibacterial activity of Haplopappus uncinatus is attributed to a new clerodane diterpenoid, 18-acetoxy-cis-cleroda-3-en-15-oic acid (10βH, 16ξ 19β, 17β, 20α form) (1), isolated as a major component from the resinous exudates of its twigs and leaves, together with the inactive 3,5-dihydroxy-6,7,3',4'-tetramethoxyflavone, n-alkanes and a few sesquiterpenoids.
Agid:
697299