PubAg

Main content area

Diagnosis of pathogen infections through analysis of nitrite production by antigen stimulated leukocytes

Author:
Waters, W.R.
Source:
United States Department of Agriculture patents 2004 no.US 6,673,566 B1
Subject:
nitrites, nitric oxide, disease diagnosis, leukocytes, immune response, bacterial antigens, tuberculosis, bacterial infections, cell-mediated immunity, animal pathogenic bacteria, Mycobacterium, Brucella, animal disease models, USDA, patents, mononuclear leukocytes, United States
Abstract:
Peripheral blood mononuclear cells which have been isolated from an animal that is infected with a microbial pathogen produce nitric oxide in response to stimulation with antigens from that pathogen. Determination of nitric oxide production in cultures of peripheral blood mononuclear cells stimulated with a pathogen's antigens may thus provide an indication of infection of the animal.
Agid:
7090
Handle:
10113/7090