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A novel l-amino acid ligase from bacillus licheniformis

Author:
Kino, Kuniki, Noguchi, Atsushi, Nakazawa, Yuji, Yagasaki, Makoto
Source:
Journal of bioscience and bioengineering 2008 v.106 no.3 pp. 313-315
ISSN:
1389-1723
Subject:
Bacillus licheniformis
Abstract:
l-Amino acid α-ligase (EC 6.3.2.28) catalyzed formation of α-peptide bond in unprotected l-amino acids in an ATP-dependent manner. BL00235 gene in Bacillus licheniformis NBRC12200 coded as a new l-amino acid ligase. BL00235 substrate specificity was strict; only methionine or leucine was acceptable as dipeptide N-terminal residues.