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Fusarium sporotrichioides strains for production of lycopene
- Jones, J.D., Hohn, T.M., Leathers, T.D.
- United States Department of Agriculture patents 2004 no.US 6,696,282 B2
- Pantoea ananatis, phytoene synthase, bacterial proteins, transgenes, molecular cloning, genetic transformation, gene expression, genetic vectors, polymerase chain reaction, oligonucleotides, restriction endonucleases, active sites, Fusarium sporotrichioides, plant pathogenic fungi, lycopene, carotenoids, nucleotide sequences, patents, USDA, United States
- The instant invention is drawn towards transformed strains of Fusarium sporotrichioides effective for the production of lycopene. The transformed strains comprise an expression cassette having three genes encoding, respectively, geranylgeranyl-pyrophosphate synthase, phytoene synthase and phytoene desaturase (i.e. Tri5crtE, Tri5crtB and Tri5crtl). The transformed strains of Fusarium sporotrichioides of the instant invention produce lycopene at levels of up to 0.5 milligrams per gram culture dry weight.