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Usefulness of C-reactive protein, serum amyloid A component, and haptoglobin determinations in bitches with pyometra for monitoring early post-ovariohysterectomy complications

Author:
Dąbrowski, R., Kostro, K., Lisiecka, U., Szczubiał, M., Krakowski, L.
Source:
Theriogenology 2009 v.72 no.4 pp. 471-476
ISSN:
0093-691X
Subject:
pyometra, tissue repair, C-reactive protein, postoperative care, monitoring, biomarkers, dogs, postoperative complications, Staphylococcus, spaying, haptoglobins, infection, Escherichia coli
Abstract:
The aim of this study was to assess changes in serum concentrations of C-reactive protein (CRP), serum amyloid A component (SAA), and haptoglobin (Hp) in bitches with pyometra undergoing ovariohysterectomy that developed postoperative wound infection-related complications. The study revealed that difficulties in postoperative wound healing were induced by infections with Escherichia coli and Staphylococcus spp. leading to re-increased levels of CRP and SAA immediately after surgery and persistently high Hp levels throughout the experiment. Our results indicate that acute-phase proteins in bitches undergoing surgery because of pyometra are useful markers for monitoring the postoperative period. Moreover, they enable prompt therapeutic management once complications develop.
Agid:
761862