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Molecular insights into the biochemical functions and signalling mechanisms of plant NLRs

Author:
Xiaoxiao Liu, Li Wan
Source:
Molecular plant pathology 2022 v.23 no.6 pp. 772-780
ISSN:
1464-6722
Subject:
cell death, immunity, pathogens, plant pathology
Abstract:
Plant intracellular immune receptors known as NLR (nucleotide‐binding leucine‐rich repeat) proteins confer immunity and cause cell death. Plant NLR proteins that directly or indirectly recognize pathogen effector proteins to initiate immune signalling are regarded as sensor NLRs. Some NLR protein families function downstream of sensor NLRs to transduce immune signalling and are known as helper NLRs. Recent breakthrough studies on plant NLR protein structures and biochemical functions greatly advanced our understanding of NLR biology. Comprehensive and detailed knowledge on NLR biology requires future efforts to solve more NLR protein structures and investigate the signalling events between sensor and helper NLRs, and downstream of helper NLRs.
Agid:
7771432