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Absorption, metabolism, and functions of hyaluronic acid and its therapeutic prospects in combination with microorganisms: A review

Author:
Xueli Zheng, Botao Wang, Xin Tang, Bingyong Mao, Qiuxiang Zhang, Tianmeng Zhang, Jianxin Zhao, Shumao Cui, Wei Chen
Source:
Carbohydrate polymers 2023 v.299 pp. 120153
ISSN:
0144-8617
Subject:
absorption, arthritis, hyaluronic acid, intestines, metabolism, probiotics, therapeutics, xerophthalmia
Abstract:
Hyaluronic acid (HA) is key to the stability of the internal environment of tissues. HA content in tissues gradually decreases with age, causing age-related health problems. Exogenous HA supplements are used to prevent or treat these problems including skin dryness and wrinkles, intestinal imbalance, xerophthalmia, and arthritis after absorption. Moreover, some probiotics are able to promote endogenous HA synthesis and alleviate symptoms caused by HA loss, thus introducing potential preventative or therapeutic applications of HA and probiotics. Here, we review the oral absorption, metabolism, and biological function of HA as well as the potential role of probiotics and HA in increasing the efficacy of HA supplements.
Agid:
7946125