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In situ synthesis of thulium(III) hexacyanoferrate(II) nanoparticles and its application for glucose detection

Author:
Meng, Zuchao, Zheng, Jianbin, Sheng, Qinglin, Zheng, Xiaohui
Source:
Analytica chimica acta 2011 v.689 no.1 pp. 47-51
ISSN:
0003-2670
Subject:
X-radiation, biosensors, chitosan, detection limit, electrodes, glucose, iron, nanoparticles, scanning electron microscopes, scanning electron microscopy, thulium
Abstract:
Thulium hexacyanoferrate (TmHCF) nanoparticles (NPs) were in situ synthesized within the chitosan film on the electrode surface by a biocatalyzed reaction. The properties of the obtained nanoparticles are characterized with scanning electron microscope (SEM) and energy-dispersive X-ray (EDX). The optimized conditions for the formation of TmHCF NPs were 16mM Fe(CN)₆ ³⁻ and 1.5mM Tm³⁺ with an accumulation time of 20min. Based on process of in situ synthesis of TmHCF NPs, a novel biosensor for glucose was designed, and there is a linear relationship between the current response of TmHCF NPs and glucose concentration. The linear range for glucose detection was 0.02–0.4mM (r=0.9975, n=5) and 0.4–13.6mM (r=0.9935, n=10) and the detection limit was 6μM at a signal-to-noise ratio of 3.
Agid:
856894